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SWATH-MS analysis of cerebrospinal fluid to generate a robust battery of biomarkers for Alzheimer’s disease

Cerebrospinal fluid (CSF) Aβ42 and tau protein levels are established diagnostic biomarkers of Alzheimer’s disease (AD). However, their inadequacy to represent clinical efficacy in drug trials indicates the need for new biomarkers. Sequential window acquisition of all theoretical fragment ion spectr...

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Detalles Bibliográficos
Autores principales: Park, Sun Ah, Jung, Jin Myung, Park, Jun Sung, Lee, Jeong Ho, Park, Bumhee, Kim, Hyung Jun, Park, Jeong-Ho, Chae, Won Seok, Jeong, Jee Hyang, Choi, Seong Hye, Baek, Je-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198522/
https://www.ncbi.nlm.nih.gov/pubmed/32366888
http://dx.doi.org/10.1038/s41598-020-64461-y