Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear pores

Roughly 10% of eukaryotic transmembrane proteins are found on the nuclear membrane, yet how such proteins target and translocate to the nucleus remains in dispute. Most models propose transport through the nuclear pore complexes, but a central outstanding question is whether transit occurs through t...

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Detalles Bibliográficos
Autores principales: Mudumbi, Krishna C., Czapiewski, Rafal, Ruba, Andrew, Junod, Samuel L., Li, Yichen, Luo, Wangxi, Ngo, Christina, Ospina, Valentina, Schirmer, Eric C., Yang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198523/
https://www.ncbi.nlm.nih.gov/pubmed/32366843
http://dx.doi.org/10.1038/s41467-020-16033-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198523/
https://www.ncbi.nlm.nih.gov/pubmed/32366843
http://dx.doi.org/10.1038/s41467-020-16033-x

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