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Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear pores
Roughly 10% of eukaryotic transmembrane proteins are found on the nuclear membrane, yet how such proteins target and translocate to the nucleus remains in dispute. Most models propose transport through the nuclear pore complexes, but a central outstanding question is whether transit occurs through t...
Autores principales: | Mudumbi, Krishna C., Czapiewski, Rafal, Ruba, Andrew, Junod, Samuel L., Li, Yichen, Luo, Wangxi, Ngo, Christina, Ospina, Valentina, Schirmer, Eric C., Yang, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198523/ https://www.ncbi.nlm.nih.gov/pubmed/32366843 http://dx.doi.org/10.1038/s41467-020-16033-x |
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