Apoptosome-dependent myotube formation involves activation of caspase-3 in differentiating myoblasts

Caspase-2, -9, and -3 are reported to control myoblast differentiation into myotubes. This had been previously explained by phosphatidylserine exposure on apoptotic myoblasts inducing differentiation in neighboring cells. Here we show for the first time that caspase-3 is activated in the myoblasts u...

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Detalles Bibliográficos
Autores principales: H. Dehkordi, Mahshid, Tashakor, Amin, O’Connell, Enda, Fearnhead, Howard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198528/
https://www.ncbi.nlm.nih.gov/pubmed/32366831
http://dx.doi.org/10.1038/s41419-020-2502-4