Paternal restraint stress affects offspring metabolism via ATF-2 dependent mechanisms in Drosophila melanogaster germ cells

Paternal environmental factors can epigenetically influence gene expressions in offspring. We demonstrate that restraint stress, an experimental model for strong psychological stress, to fathers affects the epigenome, transcriptome, and metabolome of offspring in a MEKK1-dATF2 pathway-dependent mann...

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Detalles Bibliográficos
Autores principales: Seong, Ki-Hyeon, Ly, Nhung Hong, Katou, Yuki, Yokota, Naoko, Nakato, Ryuichiro, Murakami, Shinnosuke, Hirayama, Akiyoshi, Fukuda, Shinji, Kang, Siu, Soga, Tomoyoshi, Shirahige, Katsuhiko, Ishii, Shunsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198565/
https://www.ncbi.nlm.nih.gov/pubmed/32367035
http://dx.doi.org/10.1038/s42003-020-0935-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198565/
https://www.ncbi.nlm.nih.gov/pubmed/32367035
http://dx.doi.org/10.1038/s42003-020-0935-z

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