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Paternal restraint stress affects offspring metabolism via ATF-2 dependent mechanisms in Drosophila melanogaster germ cells
Paternal environmental factors can epigenetically influence gene expressions in offspring. We demonstrate that restraint stress, an experimental model for strong psychological stress, to fathers affects the epigenome, transcriptome, and metabolome of offspring in a MEKK1-dATF2 pathway-dependent mann...
Autores principales: | Seong, Ki-Hyeon, Ly, Nhung Hong, Katou, Yuki, Yokota, Naoko, Nakato, Ryuichiro, Murakami, Shinnosuke, Hirayama, Akiyoshi, Fukuda, Shinji, Kang, Siu, Soga, Tomoyoshi, Shirahige, Katsuhiko, Ishii, Shunsuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198565/ https://www.ncbi.nlm.nih.gov/pubmed/32367035 http://dx.doi.org/10.1038/s42003-020-0935-z |
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