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The circular RNA FAM169A functions as a competitive endogenous RNA and regulates intervertebral disc degeneration by targeting miR-583 and BTRC

Intervertebral disc degeneration (IDD) is an important factor leading to low back pain, although the underlying mechanisms remain poorly understood. In this study we examined the role of circular RNA FAM169A (circ-FAM169A) in degenerative nucleus pulposus (NP) tissues, and validated its function in...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Mu, Kun, Zhang, Bin, Sun, Chao, Zhao, Ling, Dong, Zhan-Yin, Cui, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198574/
https://www.ncbi.nlm.nih.gov/pubmed/32366862
http://dx.doi.org/10.1038/s41419-020-2543-8