anlotinib alters tumor immune microenvironment by downregulating PD-L1 expression on vascular endothelial cells

Aberrant vascular network is a hallmark of cancer. However, the role of vascular endothelial cells (VECs)-expressing PD-L1 in tumor immune microenvironment and antiangiogenic therapy remains unclear. In this study, we used the specimens of cancer patients for immunohistochemical staining to observe...

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Detalles Bibliográficos
Autores principales: Liu, Shaochuan, Qin, Tingting, Liu, Zhujun, Wang, Jing, Jia, Yanan, Feng, Yingfang, Gao, Yuan, Li, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198575/
https://www.ncbi.nlm.nih.gov/pubmed/32366856
http://dx.doi.org/10.1038/s41419-020-2511-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198575/
https://www.ncbi.nlm.nih.gov/pubmed/32366856
http://dx.doi.org/10.1038/s41419-020-2511-3

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