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Comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities

Emerging urinary biomarkers continue to show promise in evaluating lupus nephritis (LN). Here, we screen urine from active LN patients for 1129 proteins using an aptamer-based platform, followed by ELISA validation in two independent cohorts comprised of 127 inactive lupus, 107 active LN, 67 active...

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Detalles Bibliográficos
Autores principales: Stanley, Samantha, Vanarsa, Kamala, Soliman, Samar, Habazi, Deena, Pedroza, Claudia, Gidley, Gabriel, Zhang, Ting, Mohan, Shree, Der, Evan, Suryawanshi, Hemant, Tuschl, Thomas, Buyon, Jill, Putterman, Chaim, Mok, Chi Chiu, Petri, Michelle, Saxena, Ramesh, Mohan, Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198599/
https://www.ncbi.nlm.nih.gov/pubmed/32366845
http://dx.doi.org/10.1038/s41467-020-15986-3