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Super-resolution in situ analysis of active ribosomal DNA chromatin organization in the nucleolus

Ribosomal RNA (rRNA) transcription by RNA polymerase I (Pol I) is the first key step of ribosome biogenesis. While the molecular mechanisms of rRNA transcription regulation have been elucidated in great detail, the functional organization of the multicopy rRNA gene clusters (rDNA) in the nucleolus i...

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Detalles Bibliográficos
Autores principales: Maiser, Andreas, Dillinger, Stefan, Längst, Gernot, Schermelleh, Lothar, Leonhardt, Heinrich, Németh, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198602/
https://www.ncbi.nlm.nih.gov/pubmed/32366902
http://dx.doi.org/10.1038/s41598-020-64589-x