A Deleted Deletion Site in a New Vector Strain and Exceptional Genomic Stability of Plaque-Purified Modified Vaccinia Ankara (MVA)

Vectored vaccines based on highly attenuated modified vaccinia Ankara (MVA) are reported to be immunogenic, tolerant to pre-existing immunity, and able to accommodate and stably maintain very large transgenes. MVA is usually produced on primary chicken embryo fibroblasts, but production processes ba...

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Detalles Bibliográficos
Autores principales: Jordan, Ingo, Horn, Deborah, Thiele, Kristin, Haag, Lars, Fiddeke, Katharina, Sandig, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198643/
https://www.ncbi.nlm.nih.gov/pubmed/31833037
http://dx.doi.org/10.1007/s12250-019-00176-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198643/
https://www.ncbi.nlm.nih.gov/pubmed/31833037
http://dx.doi.org/10.1007/s12250-019-00176-3

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