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Organoid-Transplant Model Systems to Study the Effects of Obesity on the Pancreatic Carcinogenesis in vivo

Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related mortality among adults in developed countries. The discovery of the most common genetic alterations as well as the development of organoid models of pancreatic cancer have provided insight into the fundamental pathw...

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Detalles Bibliográficos
Autores principales: Lupo, Francesca, Piro, Geny, Torroni, Lorena, Delfino, Pietro, Trovato, Rosalinda, Rusev, Borislav, Fiore, Alessandra, Filippini, Dea, De Sanctis, Francesco, Manfredi, Marcello, Marengo, Emilio, Lawlor, Rita Teresa, Martini, Maurizio, Tortora, Giampaolo, Ugel, Stefano, Corbo, Vincenzo, Melisi, Davide, Carbone, Carmine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198708/
https://www.ncbi.nlm.nih.gov/pubmed/32411709
http://dx.doi.org/10.3389/fcell.2020.00308