Antibiotic Treatment Shapes the Antigenic Environment During Chronic TB Infection, Offering Novel Targets for Therapeutic Vaccination

The lengthy and complicated current regimen required to treat drug-susceptible tuberculosis (TB) reflects the ability of Mycobacterium tuberculosis (Mtb) to persist in host tissues. The stringent response pathway, governed by the dual (p)ppGpp synthetase/hydrolase, Rel(Mtb), is a major mechanism und...

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Detalles Bibliográficos
Autores principales: Chuang, Yu-Min, Dutta, Noton K., Gordy, James T., Campodónico, Victoria L., Pinn, Michael L., Markham, Richard B., Hung, Chien-Fu, Karakousis, Petros C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198710/
https://www.ncbi.nlm.nih.gov/pubmed/32411131
http://dx.doi.org/10.3389/fimmu.2020.00680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198710/
https://www.ncbi.nlm.nih.gov/pubmed/32411131
http://dx.doi.org/10.3389/fimmu.2020.00680

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