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Antibiotic Treatment Shapes the Antigenic Environment During Chronic TB Infection, Offering Novel Targets for Therapeutic Vaccination

The lengthy and complicated current regimen required to treat drug-susceptible tuberculosis (TB) reflects the ability of Mycobacterium tuberculosis (Mtb) to persist in host tissues. The stringent response pathway, governed by the dual (p)ppGpp synthetase/hydrolase, Rel(Mtb), is a major mechanism und...

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Detalles Bibliográficos
Autores principales:	Chuang, Yu-Min, Dutta, Noton K., Gordy, James T., Campodónico, Victoria L., Pinn, Michael L., Markham, Richard B., Hung, Chien-Fu, Karakousis, Petros C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198710/ https://www.ncbi.nlm.nih.gov/pubmed/32411131 http://dx.doi.org/10.3389/fimmu.2020.00680

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