Cargando…

Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response

Double-stranded DNA (dsDNA) sensor cyclic-GMP-AMP synthase (cGAS) along with the downstream stimulator of interferon genes (STING) acting as essential immune-surveillance mediators have become hot topics of research. The intrinsic function of the cGAS-STING pathway facilitates type-I interferon (IFN...

Descripción completa

Detalles Bibliográficos
Autores principales: Wan, Dongshan, Jiang, Wei, Hao, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198750/
https://www.ncbi.nlm.nih.gov/pubmed/32411126
http://dx.doi.org/10.3389/fimmu.2020.00615