MR1-Restricted T Cells Are Unprecedented Cancer Fighters

Non-polymorphic MHC class I-related molecule MR1 presents antigenic bacterial metabolites to mucosal-associated invariant T (MAIT) cells and self-antigens to MR1-restricted T (MR1T) cells. Both MR1-restricted T cell populations are readily identified in healthy individuals, with MAIT cells accountin...

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Detalles Bibliográficos
Autores principales: Vacchini, Alessandro, Chancellor, Andrew, Spagnuolo, Julian, Mori, Lucia, De Libero, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198878/
https://www.ncbi.nlm.nih.gov/pubmed/32411144
http://dx.doi.org/10.3389/fimmu.2020.00751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198878/
https://www.ncbi.nlm.nih.gov/pubmed/32411144
http://dx.doi.org/10.3389/fimmu.2020.00751

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