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Enrichment of Tc1 cells and T cell resistance to suppression are associated with dysglycemia in the visceral fat in human obesity

OBJECTIVE: Insulin resistance, defined as tissue inflammation leading to type 2 diabetes, is a feature of obesity. The immune system has been implicated in its pathogenesis, but the role of adaptive immunity in humans remains uncertain. Here, we aim to determine whether specific phenotypic and funct...

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Detalles Bibliográficos
Autores principales: Cardellini, Sara, Socci, Carlo, Bissolati, Massimiliano, Pindozzi, Fioralba, Giovenzana, Anna, Saibene, Alessandro, Bosi, Emanuele, Battaglia, Manuela, Petrelli, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199176/
https://www.ncbi.nlm.nih.gov/pubmed/32299896
http://dx.doi.org/10.1136/bmjdrc-2019-000772