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Enrichment of Tc1 cells and T cell resistance to suppression are associated with dysglycemia in the visceral fat in human obesity
OBJECTIVE: Insulin resistance, defined as tissue inflammation leading to type 2 diabetes, is a feature of obesity. The immune system has been implicated in its pathogenesis, but the role of adaptive immunity in humans remains uncertain. Here, we aim to determine whether specific phenotypic and funct...
Autores principales: | Cardellini, Sara, Socci, Carlo, Bissolati, Massimiliano, Pindozzi, Fioralba, Giovenzana, Anna, Saibene, Alessandro, Bosi, Emanuele, Battaglia, Manuela, Petrelli, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199176/ https://www.ncbi.nlm.nih.gov/pubmed/32299896 http://dx.doi.org/10.1136/bmjdrc-2019-000772 |
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