7-Iodo-5-aza-7-deazaguanine ribonucleoside: crystal structure, physical properties, base-pair stability and functionalization

The positional change of nitro­gen-7 of the RNA constituent guanosine to the bridgehead position-5 leads to the base-modified nucleoside 5-aza-7-de­aza­guanosine. Contrary to guanosine, this mol­ecule cannot form Hoogsteen base pairs and the Watson–Crick proton donor site N3—H becomes a proton-accep...

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Detalles Bibliográficos
Autores principales: Kondhare, Dasharath, Budow-Busse, Simone, Daniliuc, Constantin, Seela, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199197/
https://www.ncbi.nlm.nih.gov/pubmed/32367834
http://dx.doi.org/10.1107/S2053229620004684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199197/
https://www.ncbi.nlm.nih.gov/pubmed/32367834
http://dx.doi.org/10.1107/S2053229620004684

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