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Transfer posterior error probability estimation for peptide identification

BACKGROUND: In shotgun proteomics, database searching of tandem mass spectra results in a great number of peptide-spectrum matches (PSMs), many of which are false positives. Quality control of PSMs is a multiple hypothesis testing problem, and the false discovery rate (FDR) or the posterior error pr...

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Detalles Bibliográficos
Autores principales: Yi, Xinpei, Gong, Fuzhou, Fu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199311/
https://www.ncbi.nlm.nih.gov/pubmed/32366221
http://dx.doi.org/10.1186/s12859-020-3485-y