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TS: a powerful truncated test to detect novel disease associated genes using publicly available gWAS summary data

BACKGROUND: In the last decade, a large number of common variants underlying complex diseases have been identified through genome-wide association studies (GWASs). Summary data of the GWASs are freely and publicly available. The summary data is usually obtained through single marker analysis. Gene-b...

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Detalles Bibliográficos
Autores principales: Zhang, Jianjun, Guo, Xuan, Gonzales, Samantha, Yang, Jingjing, Wang, Xuexia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199321/
https://www.ncbi.nlm.nih.gov/pubmed/32366212
http://dx.doi.org/10.1186/s12859-020-3511-0