Cargando…

Inhibition of mast cell tryptase attenuates neuroinflammation via PAR-2/p38/NFκB pathway following asphyxial cardiac arrest in rats

BACKGROUND: Cardiac arrest survivors suffer from neurological dysfunction including cognitive impairment. Cerebral mast cells, the key regulators of neuroinflammation contribute to neuroinflammation-associated cognitive dysfunction. Mast cell tryptase was demonstrated to have a proinflammatory effec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ocak, Umut, Eser Ocak, Pinar, Huang, Lei, Xu, Weilin, Zuo, Yuchun, Li, Peng, Gamdzyk, Marcin, Zuo, Gang, Mo, Jun, Zhang, Guangyu, Zhang, John H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199326/ https://www.ncbi.nlm.nih.gov/pubmed/32366312 http://dx.doi.org/10.1186/s12974-020-01808-2

Ejemplares similares

Activation of retinoid X receptor by bexarotene attenuates neuroinflammation via PPARγ/SIRT6/FoxO3a pathway after subarachnoid hemorrhage in rats
por: Zuo, Yuchun, et al.
Publicado: (2019)

Mast cell tryptase and asthma
por: Zhang, M-Q., et al.
Publicado: (1997)

Mast Cell-Derived Tryptase in Geographic Atrophy
por: McLeod, D. Scott, et al.
Publicado: (2017)

A Rare Complication of Endovascular Embolization: Extruded Onyx on Trigeminal Nerve
por: Eser Ocak, Pinar, et al.
Publicado: (2018)

Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA
por: Alanazi, Sultan, et al.
Publicado: (2020)

Tryptase as a PAR-2 activator in joint inflammation
por: Kelso, EB, et al.
Publicado: (2005)

The Role of Mast Cell Specific Chymases and Tryptases in Tumor Angiogenesis
por: de Souza Junior, Devandir Antonio, et al.
Publicado: (2015)

Mast Cell Tryptase Potentiates Neutrophil Extracellular Trap Formation
por: Pejler, Gunnar, et al.
Publicado: (2021)

Serum tryptase, mast cells positive to tryptase and microvascular density evaluation in early breast cancer patients: possible translational significance
por: Marech, Ilaria, et al.
Publicado: (2014)

Neovascularization and mast cells with tryptase activity increase simultaneously in human pterygium
por: Ribatti, Domenico, et al.
Publicado: (2007)

Protective role of mouse mast cell tryptase Mcpt6 in melanoma
por: Grujic, Mirjana, et al.
Publicado: (2020)

Effects of the duration of postresuscitation hyperoxic ventilation on neurological outcome and survival in an asphyxial cardiac arrest rat model
por: Hu, Tongyi, et al.
Publicado: (2019)

Rh-relaxin-2 attenuates degranulation of mast cells by inhibiting NF-κB through PI3K-AKT/TNFAIP3 pathway in an experimental germinal matrix hemorrhage rat model
por: Li, Peng, et al.
Publicado: (2020)

Effects of Secreted Mast Cell Mediators on Retinal Pigment Epithelial Cells: Focus on Mast Cell Tryptase
por: Arai, Rei, et al.
Publicado: (2017)

Peroxisomal Dysfunction Contributes to White Matter Injury Following Subarachnoid Hemorrhage in Rats via Thioredoxin-Interacting Protein-Dependent Manner
por: Xu, Weilin, et al.
Publicado: (2020)

The release of tryptase from mast cells promote tumor cell metastasis via exosomes
por: Xiao, Hui, et al.
Publicado: (2019)

Contribution of Experimental Animal Research Studies to the Emergency Medicine Literature
por: Ocak, Umut, et al.
Publicado: (2019)

Targeting Mast Cells Tryptase in Tumor Microenvironment: A Potential Antiangiogenetic Strategy
por: Ammendola, Michele, et al.
Publicado: (2014)

Tryptase Regulates the Epigenetic Modification of Core Histones in Mast Cell Leukemia Cells
por: Alanazi, Sultan, et al.
Publicado: (2021)

Mast Cell Tryptase and Carboxypeptidase A3 in the Formation of Ovarian Endometrioid Cysts
por: Atiakshin, Dmitri, et al.
Publicado: (2023)

Correlation between Serum Tryptase, Mast Cells Positive to Tryptase and Microvascular Density in Colo-Rectal Cancer Patients: Possible Biological-Clinical Significance
por: Ammendola, Michele, et al.
Publicado: (2014)

Mast Cells and Neuroinflammation
por: Dong, Hongquan, et al.
Publicado: (2014)

Correlation of IL-18 with Tryptase in Atopic Asthma and Induction of Mast Cell Accumulation by IL-18
por: Wang, Junling, et al.
Publicado: (2016)

Mast cells and mast cell tryptase enhance migration of human lung fibroblasts through protease-activated receptor 2
por: Bagher, Mariam, et al.
Publicado: (2018)

The role of mast cell tryptases in cardiac myxoma: Histogenesis and development of a challenging tumor
por: DONATO, GIUSEPPE, et al.
Publicado: (2014)

Histamine, mast cell tryptase and post-exercise hypotension in healthy and collapsed marathon runners
por: Parsons, I. T., et al.
Publicado: (2021)

Detection of clonal mast cell disease in wasp venom allergic patients with normal tryptase
por: Onnes, Merel C., et al.
Publicado: (2022)

Tryptase-Positive Mast Cells Promote Adipose Fibrosis in Secondary Lymphedema through PDGF
por: Nuri, Takashi, et al.
Publicado: (2023)

Selective autophagy as a therapeutic target for neurological diseases
por: Xu, Weilin, et al.
Publicado: (2020)

C-Kit receptor and tryptase expressing mast cells correlate with angiogenesis in breast cancer patients
por: Marech, Ilaria, et al.
Publicado: (2017)

Mast cells are important regulator of acupoint sensitization via the secretion of tryptase, 5-hydroxytryptamine, and histamine
por: Ding, Ning, et al.
Publicado: (2018)

Correction to: Histamine, mast cell tryptase and post-exercise hypotension in healthy and collapsed marathon runners
por: Parsons, I. T., et al.
Publicado: (2021)

Mast Cell Proteases Tryptase and Chymase Induce Migratory and Morphological Alterations in Bronchial Epithelial Cells
por: Berlin, Frida, et al.
Publicado: (2021)

Mast cell tryptase enhances wound healing by promoting migration in human bronchial epithelial cells
por: Mogren, Sofia, et al.
Publicado: (2021)

Inhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest
por: Huang, Lei, et al.
Publicado: (2019)

Evaluation of Timing and Route of Epinephrine in a Neonatal Model of Asphyxial Arrest
por: Vali, Payam, et al.
Publicado: (2017)

Neutrophilia, gelatinase release and microvascular leakage induced by human mast cell tryptase in a mouse model: Lack of a role of protease‐activated receptor 2 (PAR2)
por: Khedr, M. E. M. S., et al.
Publicado: (2018)

Melanocortin 1 receptor attenuates early brain injury following subarachnoid hemorrhage by controlling mitochondrial metabolism via AMPK/SIRT1/PGC-1α pathway in rats
por: Xu, Weilin, et al.
Publicado: (2021)

Resection of a Lower Clival Meningioma via Posterolateral Approach: Two-Dimensional Operative Video
por: Ocak, Pinar E., et al.
Publicado: (2021)

Skin Tags: A Link Between Lesional Mast Cell Count/Tryptase Expression and Obesity and Dyslipidemia
por: Salem, Samar Abdallah M, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_erj6j2ca8bgkqthnbt0p56q1bp