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Pre-transplant MRD negativity predicts favorable outcomes of CAR-T therapy followed by haploidentical HSCT for relapsed/refractory acute lymphoblastic leukemia: a multi-center retrospective study

BACKGROUND: Consolidative allogeneic hematopoietic stem cell transplantation is a controversial option for patients with relapsed/refractory acute lymphoblastic leukemia after chimeric antigen receptor T cell (CAR-T) therapy. We performed a multicenter retrospective study to assess whether patients...

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Detalles Bibliográficos
Autores principales: Zhao, Houli, Wei, Jieping, Wei, Guoqing, Luo, Yi, Shi, Jimin, Cui, Qu, Zhao, Mingfeng, Liang, Aibin, Zhang, Qing, Yang, Jianmin, Li, Xin, Chen, Jing, Song, Xianmin, Jing, Hongmei, Li, Yuhua, Hao, Siguo, Wu, Wenjun, Tan, Yamin, Yu, Jian, Zhao, Yanmin, Lai, Xiaoyu, Yin, Elaine Tan Su, Wei, Yunxiong, Li, Ping, Huang, Jing, Wang, Tao, Blaise, Didier, Xiao, Lei, Chang, Alex H., Nagler, Arnon, Mohty, Mohamad, Huang, He, Hu, Yongxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199358/
https://www.ncbi.nlm.nih.gov/pubmed/32366260
http://dx.doi.org/10.1186/s13045-020-00873-7