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Prediction model construction of mouse stem cell pluripotency using CpG and non-CpG DNA methylation markers

BACKGROUND: Genome-wide studies of DNA methylation across the epigenetic landscape provide insights into the heterogeneity of pluripotent embryonic stem cells (ESCs). Differentiating into embryonic somatic and germ cells, ESCs exhibit varying degrees of pluripotency, and epigenetic changes occurring...

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Detalles Bibliográficos
Autores principales: Joe, Soobok, Nam, Hojung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199378/
https://www.ncbi.nlm.nih.gov/pubmed/32366211
http://dx.doi.org/10.1186/s12859-020-3448-3