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Silencing of LncRNA PVT1 inhibits the proliferation, migration and fibrosis of high glucose-induced mouse mesangial cells via targeting microRNA-93-5p

Objective: The present study aimed to investigate the regulatory role of long non-coding RNA plasmacytoma variant translocation 1 (PVT1) on high glucose (HG)-induced mouse mesangial cells (MMCs). Methods: PVT1 expression in diabetic nephropathy (DN) mice and HG-induced MMCs was detected by qRT-PCR....

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Detalles Bibliográficos
Autores principales: Li, Jianzhou, Zhao, Qing, Jin, Xiaohong, Li, Yanhua, Song, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199453/
https://www.ncbi.nlm.nih.gov/pubmed/32329508
http://dx.doi.org/10.1042/BSR20194427