The Immunotherapeutic Effect of SIRPα-Silenced DCs against Cervical Cancer

Signal regulatory protein α (SIRPα), a transmembrane protein that is predominantly expressed in dendritic cells (DCs) or macrophages, interacts with CD47 that is overexpressed in almost all types of tumor cells. The interaction between SIRPα and CD47 leads to a negative signal that prevents the phen...

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Detalles Bibliográficos
Autores principales: Li, Xiaojie, Zhou, Wenying, Liang, Yanlan, Xu, Changzhi, Xie, Zhizhi, Liang, Jiayin, Hu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199593/
https://www.ncbi.nlm.nih.gov/pubmed/32411788
http://dx.doi.org/10.1155/2020/1705187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199593/
https://www.ncbi.nlm.nih.gov/pubmed/32411788
http://dx.doi.org/10.1155/2020/1705187

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