IQGAP1 Negatively Regulates HIV-1 Gag Trafficking and Virion Production

IQGAP1 is a master regulator of many cellular processes, including intracellular vesicle trafficking and endocytosis. We show that depletion of IQGAP1 in a variety of cell types increases the release of HIV-1 infectious virions and that overexpression diminishes virion production, with neither affec...

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Detalles Bibliográficos
Autores principales: Sabo, Yosef, de los Santos, Kenia, Goff, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199802/
https://www.ncbi.nlm.nih.gov/pubmed/32209469
http://dx.doi.org/10.1016/j.celrep.2020.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199802/
https://www.ncbi.nlm.nih.gov/pubmed/32209469
http://dx.doi.org/10.1016/j.celrep.2020.03.002

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