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IQGAP1 Negatively Regulates HIV-1 Gag Trafficking and Virion Production
IQGAP1 is a master regulator of many cellular processes, including intracellular vesicle trafficking and endocytosis. We show that depletion of IQGAP1 in a variety of cell types increases the release of HIV-1 infectious virions and that overexpression diminishes virion production, with neither affec...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199802/ https://www.ncbi.nlm.nih.gov/pubmed/32209469 http://dx.doi.org/10.1016/j.celrep.2020.03.002 |