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Progesterone receptor promotes degradation of STAT2 to inhibit the interferon response in breast cancer

Type I (IFNα/β) interferon signaling represents a critical transduction pathway involved in recognition and destruction of nascent tumor cells. Downregulation of this pathway to promote a more immunosuppressed microenvironment contributes to the ability of tumor cells to evade the immune system, a k...

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Detalles Bibliográficos
Autores principales: Walter, Katherine R., Balko, Justin M., Hagan, Christy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199813/
https://www.ncbi.nlm.nih.gov/pubmed/32391191
http://dx.doi.org/10.1080/2162402X.2020.1758547