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Progesterone receptor promotes degradation of STAT2 to inhibit the interferon response in breast cancer
Type I (IFNα/β) interferon signaling represents a critical transduction pathway involved in recognition and destruction of nascent tumor cells. Downregulation of this pathway to promote a more immunosuppressed microenvironment contributes to the ability of tumor cells to evade the immune system, a k...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199813/ https://www.ncbi.nlm.nih.gov/pubmed/32391191 http://dx.doi.org/10.1080/2162402X.2020.1758547 |