Cargando…
Progesterone receptor promotes degradation of STAT2 to inhibit the interferon response in breast cancer
Type I (IFNα/β) interferon signaling represents a critical transduction pathway involved in recognition and destruction of nascent tumor cells. Downregulation of this pathway to promote a more immunosuppressed microenvironment contributes to the ability of tumor cells to evade the immune system, a k...
Autores principales: | Walter, Katherine R., Balko, Justin M., Hagan, Christy R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199813/ https://www.ncbi.nlm.nih.gov/pubmed/32391191 http://dx.doi.org/10.1080/2162402X.2020.1758547 |
Ejemplares similares
-
Molecular determinants of context-dependent progesterone receptor action in breast cancer
por: Hagan, Christy R, et al.
Publicado: (2014) -
Progesterone promotes immunomodulation and tumor development in the murine mammary gland
por: Werner, Lauryn R, et al.
Publicado: (2021) -
A Common Docking Domain in Progesterone Receptor-B links DUSP6 and CK2 signaling to proliferative transcriptional programs in breast cancer cells
por: Hagan, Christy R., et al.
Publicado: (2013) -
MEK inhibition activates STAT signaling to increase breast cancer immunogenicity via MHC-I expression
por: Franklin, Derek A., et al.
Publicado: (2020) -
Zika virus NS2A inhibits interferon signaling by degradation of STAT1 and STAT2
por: Fanunza, Elisa, et al.
Publicado: (2021)