FMNL2 regulates dynamics of fascin in filopodia

Filopodia are peripheral F-actin–rich structures that enable cell sensing of the microenvironment. Fascin is an F-actin–bundling protein that plays a key role in stabilizing filopodia to support efficient adhesion and migration. Fascin is also highly up-regulated in human cancers, where it increases...

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Detalles Bibliográficos
Autores principales: Pfisterer, Karin, Levitt, James, Lawson, Campbell D., Marsh, Richard J., Heddleston, John M., Wait, Eric, Ameer-Beg, Simon Morris, Cox, Susan, Parsons, Maddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199847/
https://www.ncbi.nlm.nih.gov/pubmed/32294157
http://dx.doi.org/10.1083/jcb.201906111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199847/
https://www.ncbi.nlm.nih.gov/pubmed/32294157
http://dx.doi.org/10.1083/jcb.201906111

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