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FMNL2 regulates dynamics of fascin in filopodia
Filopodia are peripheral F-actin–rich structures that enable cell sensing of the microenvironment. Fascin is an F-actin–bundling protein that plays a key role in stabilizing filopodia to support efficient adhesion and migration. Fascin is also highly up-regulated in human cancers, where it increases...
Autores principales: | Pfisterer, Karin, Levitt, James, Lawson, Campbell D., Marsh, Richard J., Heddleston, John M., Wait, Eric, Ameer-Beg, Simon Morris, Cox, Susan, Parsons, Maddy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199847/ https://www.ncbi.nlm.nih.gov/pubmed/32294157 http://dx.doi.org/10.1083/jcb.201906111 |
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