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GRAF2, WDR44, and MICAL1 mediate Rab8/10/11–dependent export of E-cadherin, MMP14, and CFTR ΔF508

In addition to the classical pathway of secretion, some transmembrane proteins reach the plasma membrane through alternative routes. Several proteins transit through endosomes and are exported in a Rab8-, Rab10-, and/or Rab11-dependent manner. GRAFs are membrane-binding proteins associated with tubu...

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Detalles Bibliográficos
Autores principales: Lucken-Ardjomande Häsler, Safa, Vallis, Yvonne, Pasche, Mathias, McMahon, Harvey T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199855/
https://www.ncbi.nlm.nih.gov/pubmed/32344433
http://dx.doi.org/10.1083/jcb.201811014