High expression of JC polyomavirus-encoded microRNAs in progressive multifocal leukoencephalopathy tissues and its repressive role in virus replication

JC polyomavirus (JCPyV, JCV) causes progressive multifocal leukoencephalopathy (PML) in immunocompromised hosts. JCPyV replicates in oligodendrocytes within the brain tissue of patients with PML. The JCPyV genome encodes a microRNA (miRNA) in the region encoding the large T antigen. JCPyV-encoded mi...

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Detalles Bibliográficos
Autores principales: Takahashi, Kenta, Sato, Yuko, Sekizuka, Tsuyoshi, Kuroda, Makoto, Suzuki, Tadaki, Hasegawa, Hideki, Katano, Harutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200015/
https://www.ncbi.nlm.nih.gov/pubmed/32324824
http://dx.doi.org/10.1371/journal.ppat.1008523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200015/
https://www.ncbi.nlm.nih.gov/pubmed/32324824
http://dx.doi.org/10.1371/journal.ppat.1008523

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