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Synergistic and antagonistic drug interactions in the treatment of systemic fungal infections

Invasive fungal infections cause 1.6 million deaths annually, primarily in immunocompromised individuals. Mortality rates are as high as 90% due to limited treatments. The azole class antifungal, fluconazole, is widely available and has multi-species activity but only inhibits growth instead of kill...

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Detalles Bibliográficos
Autores principales: Wambaugh, Morgan A, Denham, Steven T, Ayala, Magali, Brammer, Brianna, Stonhill, Miekan A, Brown, Jessica CS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200157/
https://www.ncbi.nlm.nih.gov/pubmed/32367801
http://dx.doi.org/10.7554/eLife.54160