Cargando…

Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs

Cation-chloride-cotransporters (CCCs) catalyze transport of Cl(-) with K(+) and/or Na(+)across cellular membranes. CCCs play roles in cellular volume regulation, neural development and function, audition, regulation of blood pressure, and renal function. CCCs are targets of clinically important drug...

Descripción completa

Detalles Bibliográficos
Autores principales: Reid, Michelle S, Kern, David M, Brohawn, Stephen Graf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200160/
https://www.ncbi.nlm.nih.gov/pubmed/32286222
http://dx.doi.org/10.7554/eLife.52505