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Discovery of alternative polyadenylation dynamics from single cell types

Alternative polyadenylation (APA) occurs in the process of mRNA maturation by adding a poly(A) tail at different locations, resulting increased diversity of mRNA isoforms and contributing to the complexity of gene regulatory network. Benefit from the development of high-throughput sequencing technol...

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Detalles Bibliográficos
Autores principales: Ye, Congting, Lin, Juncheng, Li, Qingshun Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200215/
https://www.ncbi.nlm.nih.gov/pubmed/32382395
http://dx.doi.org/10.1016/j.csbj.2020.04.009