Blocking CTGF/CCN2 reduces established skeletal muscle fibrosis in a rat model of overuse injury

Tissue fibrosis is a hallmark of overuse musculoskeletal injuries and contributes to functional declines. We tested whether inhibition of CCN2 (cellular communication network factor 2, previously known as connective tissue growth factor, CTGF) using a specific antibody (termed FG‐3019 or pamrevlumab...

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Detalles Bibliográficos
Autores principales: Barbe, Mary F., Hilliard, Brendan A., Amin, Mamta, Harris, Michele Y., Hobson, Lucas J., Cruz, Geneva E., Popoff, Steven N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200299/
https://www.ncbi.nlm.nih.gov/pubmed/32227398
http://dx.doi.org/10.1096/fj.202000240RR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200299/
https://www.ncbi.nlm.nih.gov/pubmed/32227398
http://dx.doi.org/10.1096/fj.202000240RR

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