Dynamic Malignant Wave of Ribosome-Insulted Gut Niche via the Wnt-CTGF/CCN2 Circuit

Stress-driven ribosome dysfunction triggers an eIF2α-mediated integrated stress response to maintain cellular homeostasis. Among four key eIF2α kinases, protein kinase R (PKR) expression positively associates with poor prognoses for colorectal cancer (CRC) patients. We identified PKR-linked Wnt sign...

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Detalles Bibliográficos
Autores principales: Kim, Ki Hyung, Lee, Seung Joon, Kim, Juil, Moon, Yuseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200318/
https://www.ncbi.nlm.nih.gov/pubmed/32361596
http://dx.doi.org/10.1016/j.isci.2020.101076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200318/
https://www.ncbi.nlm.nih.gov/pubmed/32361596
http://dx.doi.org/10.1016/j.isci.2020.101076

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