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Differential effects of ‘resurrecting' Csp pseudoproteases during Clostridioides difficile spore germination

Clostridioides difficile is a spore-forming bacterial pathogen that is the leading cause of hospital-acquired gastroenteritis. C. difficile infections begin when its spore form germinates in the gut upon sensing bile acids. These germinants induce a proteolytic signaling cascade controlled by three...

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Detalles Bibliográficos
Autores principales: Donnelly, M. Lauren, Forster, Emily R., Rohlfing, Amy E., Shen, Aimee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200643/
https://www.ncbi.nlm.nih.gov/pubmed/32242623
http://dx.doi.org/10.1042/BCJ20190875