I-BET726 suppresses human skin squamous cell carcinoma cell growth in vitro and in vivo

Bromodomain-containing protein 4 (BRD4) is a potential therapeutic target of skin squamous cell carcinoma (SCC). I-BET726 is a novel BRD4 inhibitor. Its potential effect in skin SCC cells was tested in the present study. We show that I-BET726 potently inhibited survival, proliferation, cell cycle pr...

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Detalles Bibliográficos
Autores principales: Liu, Zhengjun, Li, Ping, Yang, Yong-qiang, Cai, Shang, Lin, Xiangwei, Chen, Min-bin, Guo, Hailei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200671/
https://www.ncbi.nlm.nih.gov/pubmed/32371868
http://dx.doi.org/10.1038/s41419-020-2515-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200671/
https://www.ncbi.nlm.nih.gov/pubmed/32371868
http://dx.doi.org/10.1038/s41419-020-2515-z

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