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I-BET726 suppresses human skin squamous cell carcinoma cell growth in vitro and in vivo
Bromodomain-containing protein 4 (BRD4) is a potential therapeutic target of skin squamous cell carcinoma (SCC). I-BET726 is a novel BRD4 inhibitor. Its potential effect in skin SCC cells was tested in the present study. We show that I-BET726 potently inhibited survival, proliferation, cell cycle pr...
Autores principales: | Liu, Zhengjun, Li, Ping, Yang, Yong-qiang, Cai, Shang, Lin, Xiangwei, Chen, Min-bin, Guo, Hailei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200671/ https://www.ncbi.nlm.nih.gov/pubmed/32371868 http://dx.doi.org/10.1038/s41419-020-2515-z |
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