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Quantification of tRNA fragments by electrochemical direct detection in small volume biofluid samples

Elevated levels of transfer RNA (tRNA) fragments were recently identified in plasma samples from people with epilepsy in advance of a seizure, indicting a potential novel class of circulating biomarker. Current methods for detection and quantitation of tRNA fragments (tRFs) include northern blotting...

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Detalles Bibliográficos
Autores principales: McArdle, Hazel, Hogg, Marion C., Bauer, Sebastian, Rosenow, Felix, Prehn, Jochen H. M., Adamson, Kellie, Henshall, David C., Spain, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200677/
https://www.ncbi.nlm.nih.gov/pubmed/32371908
http://dx.doi.org/10.1038/s41598-020-64485-4