Endothelial Twist1-PDGFB signaling mediates hypoxia-induced proliferation and migration of αSMA-positive cells

Remodeling of distal pulmonary arterioles (PAs) associated with marked accumulation of pulmonary artery smooth muscle cells (PASMCs) represents one of the major pathologic features of pulmonary hypertension (PH). We have reported that the transcription factor Twist1 mediates hypoxia-induced PH. Howe...

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Detalles Bibliográficos
Autores principales: Mammoto, Akiko, Hendee, Kathryn, Muyleart, Megan, Mammoto, Tadanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200682/
https://www.ncbi.nlm.nih.gov/pubmed/32371931
http://dx.doi.org/10.1038/s41598-020-64298-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200682/
https://www.ncbi.nlm.nih.gov/pubmed/32371931
http://dx.doi.org/10.1038/s41598-020-64298-5

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