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Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors

Compared to adult carcinomas, there is a paucity of targeted treatments for solid tumors in children, adolescents, and young adults (C-AYA). The impact of germline genomic signatures has implications for heritability, but its impact on targeted therapies has not been fully appreciated. Performing va...

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Detalles Bibliográficos
Autores principales: Akhavanfard, Sara, Padmanabhan, Roshan, Yehia, Lamis, Cheng, Feixiong, Eng, Charis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200683/
https://www.ncbi.nlm.nih.gov/pubmed/32371905
http://dx.doi.org/10.1038/s41467-020-16067-1