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The mechanism of loop C-neonicotinoid interactions at insect nicotinic acetylcholine receptor α1 subunit predicts resistance emergence in pests

Neonicotinoids selectively modulate insect nicotinic acetylcholine receptors (insect nAChRs). Studies have shown that serine with ability to form a hydrogen bond in loop C of some insect nAChR α subunits and glutamate with a negative charge at the corresponding position in vertebrate nAChRs may cont...

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Detalles Bibliográficos
Autores principales: Shimada, Shota, Kamiya, Masaki, Shigetou, Sho, Tomiyama, Kakeru, Komori, Yuma, Magara, Leo, Ihara, Makoto, Matsuda, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200709/
https://www.ncbi.nlm.nih.gov/pubmed/32371996
http://dx.doi.org/10.1038/s41598-020-64258-z