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Transcriptional profiling of murine macrophages stimulated with cartilage fragments revealed a strategy for treatment of progressive osteoarthritis

Accumulating evidence suggests that synovitis is associated with osteoarthritic process. Macrophages play principal role in development of synovitis. Our earlier study suggests that interaction between cartilage fragments and macrophages exacerbates osteoarthritic process. However, molecular mechani...

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Detalles Bibliográficos
Autores principales: Hamasaki, Masanari, Terkawi, Mohamad Alaa, Onodera, Tomohiro, Tian, Yuan, Ebata, Taku, Matsumae, Gen, Alhasan, Hend, Takahashi, Daisuke, Iwasaki, Norimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200748/
https://www.ncbi.nlm.nih.gov/pubmed/32371954
http://dx.doi.org/10.1038/s41598-020-64515-1