Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes

Flaviviruses, including Zika virus (ZIKV), utilise host mRNA degradation machinery to produce subgenomic flaviviral RNA (sfRNA). In mammalian hosts, this noncoding RNA facilitates replication and pathogenesis of flaviviruses by inhibiting IFN-signalling, whereas the function of sfRNA in mosquitoes r...

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Detalles Bibliográficos
Autores principales: Slonchak, Andrii, Hugo, Leon E., Freney, Morgan E., Hall-Mendelin, Sonja, Amarilla, Alberto A., Torres, Francisco J., Setoh, Yin Xiang, Peng, Nias Y. G., Sng, Julian D. J., Hall, Roy A., van den Hurk, Andrew F., Devine, Gregor J., Khromykh, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200751/
https://www.ncbi.nlm.nih.gov/pubmed/32371874
http://dx.doi.org/10.1038/s41467-020-16086-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200751/
https://www.ncbi.nlm.nih.gov/pubmed/32371874
http://dx.doi.org/10.1038/s41467-020-16086-y

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