Tuning the Binding Affinity of Heme-Responsive Biosensor for Precise and Dynamic Pathway Regulation

Current challenge for dynamic pathway control in metabolic engineering is enabling the components of the artificial regulatory system to be tunable. Here, we designed and built a heme-responsive regulatory system containing a heme biosensor HrtR and CRISPRi to regulate chemicals production while mai...

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Detalles Bibliográficos
Autores principales: Zhang, Jian, Wang, Zhiguo, Su, Tianyuan, Sun, Huanhuan, Zhu, Yuan, Qi, Qingsheng, Wang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200772/
https://www.ncbi.nlm.nih.gov/pubmed/32371371
http://dx.doi.org/10.1016/j.isci.2020.101067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200772/
https://www.ncbi.nlm.nih.gov/pubmed/32371371
http://dx.doi.org/10.1016/j.isci.2020.101067

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