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Process for an efficient lentiviral cell transduction

The combination of lentiviruses with techniques such as CRISPR-Cas9 has resulted in efficient and precise processes for targeted genome modification. An often-limiting aspect, however, is the efficiency of cell transduction. Low efficiencies with particular cell types and/or the high complexity of l...

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Detalles Bibliográficos
Autores principales: Pirona, Anna Chiara, Oktriani, Risky, Boettcher, Michael, Hoheisel, Jörg D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200879/
https://www.ncbi.nlm.nih.gov/pubmed/32395634
http://dx.doi.org/10.1093/biomethods/bpaa005